Anticancer agent 173

• Description :

  Anticancer agent 173 (compound 19) is a potent thioxodihydroquinazolinone analogs when combined with platinum drugs in inducing apoptotic cancer cells death[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  Apoptosis

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Infection

• Assay Protocol :

  https://www.medchemexpress.com/anticancer-agent-173.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1N(C2=CC=CC=C2CC)C(NC3=C1C=CC=C3)=S

• Molecular Formula :

  C16H14N2OS

• Molecular Weight :

  282.36

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

• References & Citations :

  [1]Jing Ma, et al. Combination of a thioxodihydroquinazolinone with cisplatineliminates ovarian cancer stem cell-like cells (CSC-LCs) andshows preclinical potential. Oncotarget. 2017 Dec 26;9 (5) :6042-6054.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [177951-34-7]