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Mp-polymer ester

CAT: 0804-HY-128970Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-128970Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mp-polymer ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
UNSPSC
12352203
Hazard Statement
H302-H315-H319-H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mp-polymer-ester.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCC(NCCOCCOCCC(NCCNC(CCNC(OCC(OCCC(CO)OC(CO)OCCC(CO)OC(COC(NCCC(O)=O)=O)OCCC(CO)OC(COC(NCCC(NCCNC(CCOCCOCCNC(CCN2C(C=CC2=O)=O)=O)=O)=O)=O)OCCC(CO)OC(COC(NCCC(N[C@H](C(OCCCNC([C@@H](NC([C@@H]([C@H]([C@@H]3N(CCC3)C(C[C@H]([C@H]([C@H](CC)C)N(C([C@@H](NC([C@H](C(C)C)N(C)C)=O)C(C)C)=O)C)OC)=O)OC)C)=O)CC4=CC=CC=C4)=O)=O)C)=O)=O)OC)OC(CO)CC)=O)=O)=O)=O)C=CC1=O
Molecular Formula
C125H209N19O50
Molecular Weight
2778.09
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Samantha Congreve, et al. Antibody drug conjugates (ADC) Current status and mapping of ADC:s in clinical programs.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker

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