Arochlor 1254

• Description :

  Arochlor 1254 is a polychlorinated biphenyl (PCB) mixture with biphenyl and 54% chlorine. Aroclor 1254 reduced cell viability and induced overproduction of intracellular reactive oxygen species in a dose-dependent manner. Arochlor 1254 exposure reduces calcium homeostasis, osteoblast differentiation and bone formation[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H373, H410

• Target :

  Reactive Oxygen Species (ROS)

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/arochlor-1254.html

• Concentration :

  83.33 μg/mL * 1.2 mL in Methanol

• Solubility :

  10 mM in DMSO

• Smiles :

  [Arochlor1254]

• Precautions :

  H302, H373, H410

• References & Citations :

  [1]R D Kimbrough, et al. Morphological changes in livers of rats fed polychlorinated biphenyls: light microscopy and ultrastructure. Arch Environ Health. 1972 Nov;25 (5) :354-64.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Solution, -20°C, 2 years

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [11097-69-1]