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Tylvalosin-d9

CAT: 0804-HY-128423ASSize: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-128423ASSize:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tylvalosin-d9 (Acetylisovaleryltylo sin-d9) is the deuterium labeled Tylvalosin. Tylvalosin is a third-generation macrolide, with anti-inflammatory property. Tylvalosin decreases the levels of IL-8, IL-6, IL-1β, PGE2, TNF-α and NO, and reduces the inflammatory cells recruitment and activation in mouse acute lung injury model[2].
Product Name Alternative
Acetylisovaleryltylo​sin-d9
UNSPSC
12352005
Target
Antibiotic; Apoptosis; Bacterial; Isotope-Labeled Compounds; NF-κB
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Apoptosis; NF-κB; Others
Field of Research
Others
Solubility
10 mM in DMSO
Smiles
CN(C)[C@H]([C@H]([C@@H](O[C@@H]1C)O[C@H]2[C@H](C[C@H](C(/C=C/C(C)=C/[C@@H]([C@H](OC(C[C@H]([C@@H]2C)OC(C)=O)=O)CC)CO[C@H]3[C@@H]([C@@H]([C@@H]([C@H](O3)C)O)OC)OC)=O)C)CC=O)O)[C@@H]1O[C@H]4C[C@@](O)([C@H]([C@@H](O4)C)OC(C([2H])([2H])C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)C
Molecular Formula
C53H78D9NO19
Molecular Weight
1051.31
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
Macrolide

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