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SAHA-OH

CAT: 0931-T73454-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T73454-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2857098-30-5
Target
Apoptosis, HDAC
Related Pathways
DNA Damage/DNA Repair, Apoptosis, Chromatin/Epigenetic
Bioactivity
SAHA-OH, a selective HDAC6 inhibitor with an IC50 of 23 nM, exhibits a 10- to 47-fold greater selectivity for HDAC6 over HDACs 1, 2, 3, and 8. It demonstrates anti-inflammatory effects and reduces macrophage apoptosis [1].
Smiles
O=C(CCCCCCC(=O)NC1=CC=C(CO)C=C1)NO
Molecular Formula
C15H22N2O4
Molecular Weight
294.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C