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Sordarin (sodium)

CAT: 0804-HY-126396Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-126396Size:1 mg
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Description
Sordarin sodium is an eEF2 inhibitor and antibiotic. Sordarin sodium's function is dependent on the diphthamide modification on eEF2. Sordarin sodium inhibits protein synthesis by preventing the binding of eEF2 to the ribosome complex. Sordarin sodium has antifungal activity[1][2].
CAS Number
463356-00-5
UNSPSC
12352005
Target
Antibiotic; CaMK; Fungal
Type
Reference compound
Related Pathways
Anti-infection; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sordarin-sodium.html
Purity
99.0
Solubility
10 mM in DMSO
Smiles
O=C(O[Na])[C@](C(C(C)C)=C[C@H]1C2)([C@]1(CO[C@@H]([C@@H](O)[C@H](O)[C@@H]3OC)O[C@@H]3C)C[C@]4([C@]5(CC[C@H]4C)[H])[H])[C@]25C=O
Molecular Formula
C27H39NaO8
Molecular Weight
514.58
References & Citations
[1]Wael Abdel-Fattah, et al. Insights into diphthamide, key diphtheria toxin effector. Toxins (Basel) . 2013 May 3;5 (5) :958-68.|[2]Biprashekhar Chakraborty, et al. Structure-based designing of sordarin derivative as potential fungicide with pan-fungal activity. J Mol Graph Model. 2016 May;66:133-42.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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