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Sordarin

CAT: 0013-GTR19279313-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19279313-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sordarin (Compound 1) is an antifungal agent that targets elongation factor 2 (EF2) and features a tetracyclic diterpene core with a norbornene system. It can be isolated from the fungus Sordaria araneosa. Sordarin exhibits potent antifungal activity against Saccharomyces cerevisiae and Candida albicans. By stabilizing the ribosome/EF2 complex, Sordarin blocks ribosomal translocation along mRNA during nascent polypeptide chain elongation, thereby inhibiting fungal protein synthesis.
CAS Number
11076-17-8
Smiles
C (O) (=O) [C@]12[C@@]3 (CO[C@H]4[C@@H] (O) [C@H] (O) [C@H] (OC) [C@@H] (C) O4) [C@] (C[C@]1 (C=O) [C@]5 ([C@] (C3) ([C@H] (C) CC5) [H]) [H]) (C=C2C (C) C) [H]
Molecular Formula
C27H40O8
Molecular Weight
492.61
Notes
For research use only.

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