Products for Research Use Only
RegisterLogin

NOC-5

CAT: 0804-HY-126166-01Size: 1 mgDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-126166-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NOC-5 is a diazeniumdiolate compound that belongs to the same family of NO donors. NOC-5 is able to increase intracellular XIAP and Aven levels, potentially leading to the inhibition of caspase-9 activity following increased mitochondrial permeability[1][2].
CAS Number
146724-82-5
UNSPSC
12352211
Hazard Statement
H242
Target
IAP
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/noc-5.html
Purity
98.50
Solubility
10 mM in DMSO
Smiles
CC(N(CCCN)N(N=O)O)C
Molecular Formula
C6H16N4O2
Molecular Weight
176.22
Precautions
H242
References & Citations
[1]Sophie A Bradley, et al. Characterisation and comparison of temporal release profiles of nitric oxide generating donors. J Neurosci Methods. 2015 Apr 30;245:116-24.|[2]Elena G Starikova, et al. Nitric oxide donor NOC-5 increases XIAP and Aven level in Jurkat cells. Cell Biol Int. 2014 Jul;38 (7) :799-802.|[3]Starikova EG, et al. Nitric oxide donor NOC-5 increases XIAP and Aven level in Jurkat cells. Cell Biol Int. 2014 Jul;38 (7) :799-802.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

1-Hydroxy-2-oxo-3-(3-aminopropyl)-3-isopropyl-1-triazene

NOC-5 is a nitroso compound that is triazane in which the nitrogen at position 1 is substituted by an isopropyl group and a 3-aminopropyl group, that at position 2 is substituted by a hydroxy group, and that at position 3 is substituted by an oxo group. It is a nitric oxide donor. It has a role as a nitric oxide donor. It is a nitroso compound, a primary amino compound and a tertiary amino compound.

CAS Number146724-82-5
PubChem CID135402057
IUPAC Name(Z)-[3-aminopropyl(propan-2-yl)amino]-hydroxyimino-oxidoazanium
Molecular FormulaC6H16N4O2
Molecular Weight176.22
XLogP0.7
Topological Polar Surface Area90.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Heavy Atom Count12
Formal Charge0
Complexity148
SMILES
CC(C)N(CCCN)/[N+](=N/O)/[O-]
InChI
InChI=1S/C6H16N4O2/c1-6(2)9(5-3-4-7)10(12)8-11/h6,11H,3-5,7H2,1-2H3/b10-8-
InChIKey
MTIRIKBRVALRPJ-NTMALXAHSA-N
Chemical Structure
2D Structure
2D structure of 1-Hydroxy-2-oxo-3-(3-aminopropyl)-3-isopropyl-1-triazene
CAS: 146724-82-5
CID: 135402057
Formula: C6H16N4O2
MW: 176.22
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight176.22
XLogP30.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass176.12732577
Monoisotopic Mass176.12732577
Topological Polar Surface Area90.6 Ų
Heavy Atom Count12
Formal Charge0
Complexity148
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-P2112-01DOTA-NOC
HY-P11318NOTA-NOC
HY-N85815,5'-Dimethoxysecoisolariciresinol
HY-N26485,5'-Dimethoxylariciresinol
HY-1494765-LOX-IN-5
HY-160457-01FABP4/5-IN-5
HY-1543445′-Deoxy-5′-iodo-5-methyluridine
HY-W037549-015,5,5-Trifluoro-DL-leucine
HY-1543465’-Azido-5’-deoxy-5-methyluridine
HY-1543454′,5′-Didehydro-5′-deoxy-5-methyluridine

Alternative Products

CatalogName
ALX-430-017-M005NOC-5
N380-10NOC 5, 10 mg
N380-12NOC 5, 50 mg
2492-50NOC-18
GTR19150243-01NOTA-NOC
GTR19236727DOTA-NOC
ALX-430-018-M005NOC-7
ALX-430-019-M010NOC-12
GTR17970097Noc Antibody

Popular Products