DOTA-NOC

• Description:

  DOTA-NOC (DOTA-Nal3-octreotide) is a high-affinity ligand of somatostatin receptor subtypes 2, 3 and 5. DOTA-NOC can be used for labeling with various radiometals, and development of radiopeptide imaging[1]. DOTA-NOC can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .

• Product Name Alternative:

  DOTA-Nal3-octreotide

• UNSPSC:

  12352209

• Target:

  Radionuclide-Drug Conjugates (RDCs) ; Somatostatin Receptor

• Type:

  Peptides

• Related Pathways:

  Antibody-drug Conjugate/ADC Related; GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/dota-noc.html

• Purity:

  99.22

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C([C@@H](NC([C@H](CSSC[C@H](NC([C@](NC([C@@H](NC1=O)CCCCN)=O)([H])[C@H](O)C)=O)C(N[C@H](CO)[C@H](O)C)=O)NC([C@H](NC(CN2CCN(CCN(CCN(CC2)CC(O)=O)CC(O)=O)CC(O)=O)=O)CC3=CC=CC=C3)=O)=O)CC4=CC=CC5=C4C=CC=C5)N[C@@H]1CC6=CNC7=CC=CC=C67

• Molecular Formula:

  C69H94N14O17S2

• Molecular Weight:

  1455.70

• References & Citations:

  [1]Wild D, et al. DOTA-NOC, a high-affinity ligand of somatostatin receptor subtypes 2, 3 and 5 for labelling with various radiometals. Eur J Nucl Med Mol Imaging. 2003 Oct;30 (10) :1338-47.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• Isoform:

  RDC Peptide

• CAS Number:

  [619300-53-7]