LY-338979

• Description :

  LY-338979 (Pemetrexed 6-oxo diacid impurity) is a metabolite of LY231514 (Pemetrexed; HY-10820) [1].

• Product Name Alternative :

  Pemetrexed 6-oxo diacid impurity

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Drug Metabolite

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ly-338979.html

• Purity :

  99.67

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(CC[C@H](NC(C1=CC=C(C=C1)CCC(C(N2)=O)C3=C2NC(N)=NC3=O)=O)C(O)=O)O

• Molecular Formula :

  C20H21N5O7

• Molecular Weight :

  443.41

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Woodland JM, et al. Metabolism and disposition of the antifolate LY231514 in mice and dogs. Drug Metab Dispos. 1997 Jun;25 (6) :693-700.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [193281-00-4]