PI3Kδ-IN-3

• UNSPSC Description:

  PI3Kδ-IN-3 (Compound 11) is a PI3Kδ inhibitor (IC50: 9 nM). PI3Kδ-IN-3 inhibits B cell function. PI3Kδ-IN-3 has good pharmacokinetic properties[1].

• Target Antigen:

  PI3K

• Type:

  Reference compound

• Related Pathways:

  PI3K/Akt/mTOR

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pi3kδ-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N#CC1=CC(C2=CC3=C(C4=CC=CC(C(N5CCN(C(C)=O)CC5)=O)=C4)N=CN=C3C=C2)=CN=C1OC

• Molecular Weight:

  492.53

• References & Citations:

  [1]Hoegenauer K, et al. Discovery and Pharmacological Characterization of Novel Quinazoline-Based PI3K Delta-Selective Inhibitors. ACS Med Chem Lett. 2016 Jun 2;7(8):762-7.

• Shipping Conditions:

  Room temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  1431540-99-6