PI3Kδ-IN-3

PI3Kδ-IN-3

• CAS Number: 1431540-99-6
• UNSPSC Description: PI3Kδ-IN-3 (Compound 11) is a PI3Kδ inhibitor (IC50: 9 nM). PI3Kδ-IN-3 inhibits B cell function. PI3Kδ-IN-3 has good pharmacokinetic properties[1].
• Target Antigen: PI3K
• Type: Reference compound
• Related Pathways: PI3K/Akt/mTOR
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pi3kδ-in-3.html
• Solubility: 10 mM in DMSO
• Smiles: N#CC1=CC(C2=CC3=C(C4=CC=CC(C(N5CCN(C(C)=O)CC5)=O)=C4)N=CN=C3C=C2)=CN=C1OC
• Molecular Weight: 492.53
• References & Citations: [1]Hoegenauer K, et al. Discovery and Pharmacological Characterization of Novel Quinazoline-Based PI3K Delta-Selective Inhibitors. ACS Med Chem Lett. 2016 Jun 2;7(8):762-7.
• Shipping Conditions: Room temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: No Development Reported