ME-3277

• Description :

  ME-3277 is a potent GPIIb/IIIa antagonist. ME-3277 reduces cerebral infarction without enhancing intracranial hemorrhage in photothrombotic occlusion of rabbit middle cerebral artery (MCA) . ME-3277 can be used for the acute cerebral infarction research[1].

• CAS Number :

  [165948-72-1]

• UNSPSC :

  12352005

• Target :

  Integrin

• Related Pathways :

  Cytoskeleton

• Field of Research :

  Neurological Disease; Cardiovascular Disease

• Smiles :

  O=C(C1=CC=C(OCC(O)=O)C(OCC(O)=O)=C1)CNC(C(S2)=CC3=C2CCNC3)=O

• Molecular Formula :

  C20H20N2O8S

• Molecular Weight :

  448.45

• References & Citations :

  [1]Kawano KI, et al. ME3277, a GPIIb/IIIa antagonist reduces cerebral infarction without enhancing intracranial hemorrhage in photothrombotic occlusion of rabbit middle cerebral artery. J Cereb Blood Flow Metab. 2000 Jun;20 (6) :988-97.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• Isoform :

  αIIbβ3