ME-1228

• Description:

  ME-1228 is an antibacterial agent and sulfur-containing analogue of OCP 9-176. ME 1228 is generally twofold more active than OCP 9-176 against Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Providencia stuartii, Proteus vulgaris, and Serratia marcescens. ME-1228 has antibacterial activity against E. coli UB 1005, P. aeruginosa K779K, and P. aeruginosa E4, with MICs of 0.25, 0.25, and 1 μg/mL, respectively[1].

• UNSPSC:

  12352005

• Target:

  Bacterial

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Smiles:

  [O-]C(C1=C(CSC2=CC=[N+](CC)C=C2)CS[C@@]([C@@H]3NC(/C(C4=CSC(N)=N4)=N\O[C@@H](C)C(O)=O)=O)([H])N1C3=O)=O

• Molecular Formula:

  C23H24N6O7S3

• Molecular Weight:

  592.67

• References & Citations:

  [1]Gu JW, et al. In vitro activity of an oxycephem OCP 9-176 compared with its sulfur analog and other beta-lactams. Diagn Microbiol Infect Dis. 1991 Mar-Apr;14 (2) :135-40.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [115369-52-3]