KM-233

• Description :

  KM-233 is a classical cannabinoid with good blood brain barrier penetration. KM-233 possesses a selective affinity for the CB2 receptors relative to THC. KM-233 is effective at reducing U87 glioma tumor burden, and can be used for glioma research[1].

• UNSPSC :

  12352005

• Target :

  Cannabinoid Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/km-233.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OC1=CC(C(C2=CC=CC=C2)(C)C)=CC3=C1[C@]4([H])CC(C)=CC[C@]4(C(C)(O3)C)[H]

• Molecular Formula :

  C25H30O2

• Molecular Weight :

  362.50

• References & Citations :

  [1]Duntsch C, et al. Safety and efficacy of a novel cannabinoid chemotherapeutic, KM-233, for the treatment of high-grade glioma. J Neurooncol. 2006 Apr;77 (2) :143-52.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [628263-22-9]