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KM-001-E2

CAT: 0804-HY-153275A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-153275A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(S) -KM-001 ((S) -KM-001) is the enantiomer of KM-001. KM-001 is a TRPV3 channel antagonist and can be used for studying skin itching and keratinosis diseases[1].
CAS Number
2682864-43-1
Product Name Alternative
(S) -KM-001
UNSPSC
12352005
Target
Drug Isomer
Related Pathways
Others
Field of Research
Others
Purity
99.08
Smiles
OCC1=C([C@H]2CN(CC2)C(C3=CC=C(C=N3)F)=O)C=CC(C4=C(C5CC5)C=CC=C4)=C1
Molecular Formula
C26H25FN2O2
Molecular Weight
416.49
References & Citations
[1]Barak SL, et al. 629 Evaluating the safety and efficacy of topical KM-001, a TRPV3 inhibitor, for treatment of pruritus in patients with Lichen Simplex Chronicus (LSC) : a first in human, double-blind, randomized vehicle-controlled study. Journal of Investigative Dermatology. 2023 May 1;143 (5) :S108.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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