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LY 293284

CAT: 0804-HY-120396Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120396Size:1 Each
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Description
LY 293284 is a potent and selective 5-HT1A receptor agonist. LY 293284 results in a significant drop in core temperature and consumes more food in cholestasis rat induced by bile duct resection[1][2].
CAS Number
141318-62-9
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ly-293284.html
Solubility
10 mM in DMSO
Smiles
CC(C1=C2C3=C(C=C1)NC=C3C[C@@H](C2)N(CCC)CCC)=O
Molecular Formula
C19H26N2O
Molecular Weight
298.42
References & Citations
[1]Marona-Lewicka D, et al. Aripiprazole (OPC-14597) fully substitutes for the 5-HT1A receptor agonist LY293284 in the drug discrimination assay in rats. Psychopharmacology (Berl) . 2004;172 (4) :415-421.|[2]Burak KW, et al. Increased midbrain 5-HT1A receptor number and responsiveness in cholestatic rats. Brain Res. 2001;892 (2) :376-379.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor

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