AL-9

• Description :

  AL-9 is a inhibitor of PI4KIIIα, with the IC50 of 0.57 μM, that can inhibit HCV replication[1].

• UNSPSC :

  12352005

• Target :

  HCV; PI4K

• Type :

  Reference compound

• Related Pathways :

  Anti-infection; PI3K/Akt/mTOR

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/al-9.html

• Purity :

  99.68

• Solubility :

  DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  OCC1=CC=C(C2=CC3=C(NC4=CC=C(N5CCOCC5)C=C4)N=CN=C3C=C2)O1

• Molecular Formula :

  C23H22N4O3

• Molecular Weight :

  402.45

• References & Citations :

  [1]Annalisa Bianco, et al. Metabolism of phosphatidylinositol 4-kinase IIIα-dependent PI4P Is subverted by HCV and is targeted by a 4-anilino quinazoline with antiviral activity. PLoS Pathog. 2012;8 (3) :e1002576.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [869218-90-6]