AL-9

• Description:

  AL-9 is a inhibitor of PI4KIIIα, with the IC50 of 0.57 μM, that can inhibit HCV replication[1].

• UNSPSC:

  12352005

• Target:

  HCV; PI4K

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; PI3K/Akt/mTOR

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/al-9.html

• Purity:

  99.68

• Solubility:

  DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  OCC1=CC=C(C2=CC3=C(NC4=CC=C(N5CCOCC5)C=C4)N=CN=C3C=C2)O1

• Molecular Formula:

  C23H22N4O3

• Molecular Weight:

  402.45

• References & Citations:

  [1]Annalisa Bianco, et al. Metabolism of phosphatidylinositol 4-kinase IIIα-dependent PI4P Is subverted by HCV and is targeted by a 4-anilino quinazoline with antiviral activity. PLoS Pathog. 2012;8 (3) :e1002576.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [869218-90-6]