MO-I-500

CAT: 0804-HY-117426Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-117426Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

MO-I-500 is a pharmacological of FTO inhibitor with an IC50 of 8.7 μM for the inhibition of purified FTO demethylase catalyzing demethylation of an artificial small methylated substrate. MO-I-500 can be used for the research of rare panresistant triple-negative inflammatory breast cancer[1].

CAS Number

1585219-04-0

UNSPSC

12352005

Target

Fat Mass and Obesity-associated Protein (FTO)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mo-i-500.html

Purity

99.10

Solubility

DMSO : 31.8 mg/mL (ultrasonic; warming)

Smiles

CCS(=O)(NC1=C(C(O)=C(O1)C2=CC=C(C=C2)Cl)O)=O

Molecular Formula

C12H12ClNO5S

Molecular Weight

317.75

References & Citations

[1]Balraj Singh et al. Important Role of FTO in the Survival of Rare Panresistant Triple-Negative Inflammatory Breast Cancer Cells Facing a Severe Metabolic Challenge. PLoS One. 2016 Jul 8;11 (7) :e0159072.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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