MO-I-500

• Description :

  MO-I-500 is a pharmacological of FTO inhibitor with an IC50 of 8.7 μM for the inhibition of purified FTO demethylase catalyzing demethylation of an artificial small methylated substrate. MO-I-500 can be used for the research of rare panresistant triple-negative inflammatory breast cancer[1].

• UNSPSC :

  12352005

• Target :

  Fat Mass and Obesity-associated Protein (FTO)

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/mo-i-500.html

• Purity :

  99.10

• Solubility :

  DMSO : 31.8 mg/mL (ultrasonic; warming)

• Smiles :

  CCS(=O)(NC1=C(C(O)=C(O1)C2=CC=C(C=C2)Cl)O)=O

• Molecular Formula :

  C12H12ClNO5S

• Molecular Weight :

  317.75

• References & Citations :

  [1]Balraj Singh et al. Important Role of FTO in the Survival of Rare Panresistant Triple-Negative Inflammatory Breast Cancer Cells Facing a Severe Metabolic Challenge. PLoS One. 2016 Jul 8;11 (7) :e0159072.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1585219-04-0]