SB-206606

• Description:

  SB-206606, a stereoisomer of BRL 37344, is a potentially specific, beta 3-adrenergic receptor (β3-AR) ligand. The affinity of [3H]SB 206606 is 76 times higher for the β3-AR than for the beta 1/beta 2-adrenergic receptors[1].

• UNSPSC:

  12352005

• Target:

  Adrenergic Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/sb-206606.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(COC1=CC=C(C=C1)C[C@@H](C)NC[C@H](O)C2=CC=CC(Cl)=C2)O

• Molecular Formula:

  C19H22ClNO4

• Molecular Weight:

  363.84

• References & Citations:

  [1]Muzzin P, et al. Characterization of a new, highly specific, beta 3-adrenergic receptor radioligand, [3H]SB 206606. Mol Pharmacol. 1994 Aug;46 (2) :357-63. PMID: 8078497.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  β adrenergic receptor

• CAS Number:

  [116049-78-6]