TMB-8

• Description :

  TMB-8 is a novel Ca 2+ antagonist. TMB-8 may exert inhibitory effects in smooth muscle by blocking Ca 2+ release from intracellular bound stores.

• CAS Number :

  [53464-72-5]

• UNSPSC :

  12352005

• Target :

  Calcium Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/tmb-8.html

• Solubility :

  10 mM in DMSO

• Smiles :

  COC1=C(C(OC)=CC(C(OCCCCCCCCN(CC)CC)=O)=C1)OC.Cl

• Molecular Formula :

  C22H38ClNO5

• Molecular Weight :

  431.99

• References & Citations :

  [1]Malagodi MH, et al. Pharmacological evaluation of a new Ca2+ antagonist, 8- (N, N-diethylamino) -octyl-3,4,5-trimethoxybenzoate hydrochloride (TMB-8) : studies in smooth muscles. Eur J Pharmacol. 1974 Jun;27 (1) :25-33.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported