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TMB

CAT: 0804-HY-15930-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-15930-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TMB is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP) . TMB can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922[1][2].
CAS Number
54827-17-7
Product Name Alternative
BM blue; Sure Blue TMB
UNSPSC
12171500
Hazard Statement
H302, H315, H319, H335
Target
Fluorescent Dye; Reactive Oxygen Species (ROS)
Type
Dye Reagents
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/TMB.html
Purity
99.95
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
NC1=C(C)C=C(C2=CC(C)=C(N)C(C)=C2)C=C1C
Molecular Formula
C16H20N2
Molecular Weight
240.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Bresolí-Obach R, et al. Tetramethylbenzidine: An Acoustogenic Photoacoustic Probe for Reactive Oxygen Species Detection. Sensors (Basel) . 2020 Oct 21;20 (20) :5952. |[2]Frey A, et al. A stable and highly sensitive 3,3',5,5'-tetramethylbenzidine-based substrate reagent for enzyme-linked immunosorbent assays. J Immunol Methods. 2000 Jan 13;233 (1-2) :47-56.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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