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Anticancer agent 39

CAT: 0804-HY-115980Size: InquireDry Ice: NoHazardous: No
CAT#:0804-HY-115980Size:Inquire
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
[9007-83-4]
UNSPSC Description
Anticancer agent 39 (compound B12), a fluorescent derivative of Jiyuan Oridonin A (JOA), induces the collapse of mitochondrial membrane potential (MMP)and thus induced apoptosis.Anticancer agent 39 inhibits cell cloning and migration.Anticancer agent 39 exhibits promising anti-proliferative activity against HGC-27 cells with IC50 value of 0.39 μM[1].
Target Antigen
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-39.html
Solubility
10 mM in DMSO
Smiles
O[C@@]([C@]1([H])C2=C)([H])[C@@]3(C2=O)[C@]([C@H](C1)O)([H])C4(CCCC(C)5C)[C@]5([H])C[C@@]3([H])O[C@H]4OCCCC(N=N6)=CN6CCOCCOCCOCCN(C7=O)C(C8=CC=C(N9CCCCC9)C%10=C8C7=CC=C%10)=O
Molecular Weight
896.08
References & Citations
[1]Chen Zhou, et al. Synthesis, biological evaluation and cellular localization study of fluorescent derivatives of Jiyuan Oridonin A. Eur J Med Chem. 2022 Feb 5;229:114048.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported

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