Sirt2-IN-5

Sirt2-IN-5

• CAS Number: 902456-47-7
• UNSPSC Description: Sirt2-IN-5 is a potent SIRT2 inhibtor[1].
• Target Antigen: Sirtuin
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: Cancer; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/sirt2-in-5.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C(C2=CC=C(Cl)C=C2)=CC(N3CCOCC3)=NN1CC(N4CCN(C5=CC=CC(Cl)=C5)CC4)=O
• Molecular Weight: 528.43
• References & Citations: [1]Sukuroglu, M.K., et al. The potential of 4-aryl-6-morpholino-3(2H)-pyridazinone-2-arylpiperazinylacetamide as a new scaffold for SIRT2 inhibition: in silico approach guided by pharmacophore mapping and molecular docking. Med Chem Res 30, 1915–1924 (2021).
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported