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Sirt2-IN-5

CAT: 0804-HY-115979Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-115979Size:1 Each
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Description
Sirt2-IN-5 is a potent SIRT2 inhibtor[1].
CAS Number
902456-47-7
UNSPSC
12352005
Target
Sirtuin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sirt2-in-5.html
Solubility
10 mM in DMSO
Smiles
O=C1C(C2=CC=C(Cl)C=C2)=CC(N3CCOCC3)=NN1CC(N4CCN(C5=CC=CC(Cl)=C5)CC4)=O
Molecular Formula
C26H27Cl2N5O3
Molecular Weight
528.43
References & Citations
[1]Sukuroglu, M.K., et al. The potential of 4-aryl-6-morpholino-3 (2H) -pyridazinone-2-arylpiperazinylacetamide as a new scaffold for SIRT2 inhibition: in silico approach guided by pharmacophore mapping and molecular docking. Med Chem Res 30, 1915–1924 (2021) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SIRT2

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