SIRT2-IN-8

• Description :

  SIRT2-IN-8 is a potent SIRT2 inhibitor. SIRT2-IN-8 can be used for Huntington’s and Parkinson’s diseases research[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H301, H315, H319, H335

• Target :

  Sirtuin

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Epigenetics

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/sirt2-in-8.html

• Purity :

  99.32

• Solubility :

  DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O=C(C1=CC=C(Cl)C=C1)N(CC2)CCN2C(C=C3)=C(C=CC=N4)C4=C3[N+]([O-])=O

• Molecular Formula :

  C20H17ClN4O3

• Molecular Weight :

  396.83

• Precautions :

  H301, H315, H319, H335

• References & Citations :

  [1]Bodner RA, Outeiro TF, Altmann S, et al. Pharmacological promotion of inclusion formation: a therapeutic approach for Huntington's and Parkinson's diseases. Proc Natl Acad Sci U S A. 2006;103 (11) :4246-4251.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  SIRT2

• CAS Number :

  [115687-05-3]