RMC-4529

• UNSPSC Description:

  RMC-4529 has an IC50 value of 1.0 nM against p-4E-BP1-(T37/46) in mTOR kinase cellular assay.

• Target Antigen:

  mTOR

• Type:

  Reference compound

• Related Pathways:

  PI3K/Akt/mTOR

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/rmc-4529.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NC1=C2C(C3=CC=C(OC(N)=N4)C4=C3)=NN(C2=NC=N1)CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCN5C=C(N=N5)CO/N=C6[C@@H]([C@@H](/C(C)=C/[C@H]([C@@H](C[C@@](OC([C@@]7([H])N(CCCC7)C(C([C@@]8(O[C@](CC[C@H]8C)([H])C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@H]/6C)C)OC)O)=O)=O)=O)([H])[C@H](C)C[C@H]9C[C@H]([C@@H](CC9)O)OC)OC)C)O)OC)=O

• Molecular Weight:

  1771.14

• References & Citations:

  [1]Semko C, et al. Rapamycin analogs as mtor inhibitors. WO2018204416A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2250059-27-7