1,2-Didecanoylglycerol

• UNSPSC Description:

  1,2-Didecanoylglycerol, a synthetic diacylglycerol, is metabolized by platelets to 1,2-didecanoylphosphatidic acid (PA10) and activates protein kinase C (PKC)[1][2].

• Target Antigen:

  PKC

• Type:

  Reference compound

• Related Pathways:

  Epigenetics;TGF-beta/Smad

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/1-2-didecanoylglycerol.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(CCCCCCCCC)OCC(CO)OC(CCCCCCCCC)=O

• Molecular Weight:

  400.59

• References & Citations:

  [1]Lapetina EG. Incorporation of synthetic 1,2-diacylglycerol into platelet phosphatidylinositol is increased by cyclic AMP. FEBS Lett. 1986;195(1-2):111-114. |[2]Negro-Vilar A, et al. 1,2-Didecanoylglycerol and phorbol 12,13-dibutyrate enhance anterior pituitary hormone secretion in vitro. Endocrinology. 1985;117(4):1559-1564.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  17863-69-3