PC-766B

• UNSPSC Description:

  PC-766B is a macrolide antibiotic. PC-766B is active against Gram-positive bacteria, and some fungi and yeasts, but inactive against Gram-negative bacteria. PC-766B shows antitumor activity against murine tumor cells. PC-766B has weak inhibitory activity against Na+, K+-ATPase[1][2].

• Target Antigen:

  Antibiotic; Bacterial; Fungal

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Infection

• Assay Protocol:

  https://www.medchemexpress.com/pc-766b.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1O[C@@H]([C@H](/C=C/C=C(C[C@@H]([C@@H]([C@@H](/C=C(/C=C1\OC)C)C)O)C)\C)OC)[C@H]([C@H]([C@H](C)[C@]2(C[C@H]([C@@H]([C@H](O2)/C=C/C=C/C)C)O[C@H]3C[C@@H](O)[C@H](O)[C@H](O3)C)O)O)C

• Molecular Weight:

  776.99

• References & Citations:

  [1]Kumagai K, et, al. PC-766B, a new macrolide antibiotic produced by Nocardia brasiliensis. I. Taxonomy, fermentation and biological activity. J Antibiot (Tokyo). 1993 Jun;46(6):972-8.|[2]Kumagai K, et, al. PC-766B, a new macrolide antibiotic produced by Nocardia brasiliensis. II. Isolation, physico-chemical properties and structure elucidation. J Antibiot (Tokyo). 1993 Jul;46(7):1139-44.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  108375-77-5