PC-766B

• Description :

  PC-766B is a macrolide antibiotic. PC-766B is active against Gram-positive bacteria, and some fungi and yeasts, but inactive against Gram-negative bacteria. PC-766B shows antitumor activity against murine tumor cells. PC-766B has weak inhibitory activity against Na+, K+-ATPase[1][2].

• Product Name Alternative :

  Antibiotic PC-766B

• UNSPSC :

  12352005

• Target :

  Antibiotic; Bacterial; Fungal

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Infection

• Assay Protocol :

  https://www.medchemexpress.com/pc-766b.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1O[C@@H]([C@H](/C=C/C=C(C[C@@H]([C@@H]([C@@H](/C=C(/C=C1\OC)C)C)O)C)\C)OC)[C@H]([C@H]([C@H](C)[C@]2(C[C@H]([C@@H]([C@H](O2)/C=C/C=C/C)C)O[C@H]3C[C@@H](O)[C@H](O)[C@H](O3)C)O)O)C

• Molecular Formula :

  C43H68O12

• Molecular Weight :

  776.99

• References & Citations :

  [1]Kumagai K, et, al. PC-766B, a new macrolide antibiotic produced by Nocardia brasiliensis. I. Taxonomy, fermentation and biological activity. J Antibiot (Tokyo) . 1993 Jun;46 (6) :972-8.|[2]Kumagai K, et, al. PC-766B, a new macrolide antibiotic produced by Nocardia brasiliensis. II. Isolation, physico-chemical properties and structure elucidation. J Antibiot (Tokyo) . 1993 Jul;46 (7) :1139-44.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Macrolide

• CAS Number :

  [108375-77-5]