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PC-766B

CAT: 0804-HY-112661Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-112661Size:1 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PC-766B is a macrolide antibiotic. PC-766B is active against Gram-positive bacteria, and some fungi and yeasts, but inactive against Gram-negative bacteria. PC-766B shows antitumor activity against murine tumor cells. PC-766B has weak inhibitory activity against Na+, K+-ATPase[1][2].
CAS Number
[108375-77-5]
Product Name Alternative
Antibiotic PC-766B
UNSPSC
12352005
Target
Antibiotic; Bacterial; Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/pc-766b.html
Solubility
10 mM in DMSO
Smiles
O=C1O[C@@H]([C@H](/C=C/C=C(C[C@@H]([C@@H]([C@@H](/C=C(/C=C1\OC)C)C)O)C)\C)OC)[C@H]([C@H]([C@H](C)[C@]2(C[C@H]([C@@H]([C@H](O2)/C=C/C=C/C)C)O[C@H]3C[C@@H](O)[C@H](O)[C@H](O3)C)O)O)C
Molecular Formula
C43H68O12
Molecular Weight
776.99
References & Citations
[1]Kumagai K, et, al. PC-766B, a new macrolide antibiotic produced by Nocardia brasiliensis. I. Taxonomy, fermentation and biological activity. J Antibiot (Tokyo) . 1993 Jun;46 (6) :972-8.|[2]Kumagai K, et, al. PC-766B, a new macrolide antibiotic produced by Nocardia brasiliensis. II. Isolation, physico-chemical properties and structure elucidation. J Antibiot (Tokyo) . 1993 Jul;46 (7) :1139-44.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Macrolide

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