c-Fms-IN-6

c-Fms-IN-6

• CAS Number: 1628574-81-1
• UNSPSC Description: c-Fms-IN-6 is a potent inhibitor of c-FMS, with an IC50 of ≤10 nM for unphosphorylated c-FMS, also weakly inhibits unphosphorylated c-KIT and PDGFR (IC50, > 1 μM). Used in the research of autoimmune diseases[1].
• Target Antigen: c-Fms
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/c-fms-in-6.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1N(C2=NC(C)=C(OC3=CC(C4=CN(CC)N=C4)=NC=C3)C=C2)N=C(C(C)(C)C)N1
• Molecular Weight: 419.48
• References & Citations: [1]Gary E. L. BRANDT, et al. 1,2,4-triazol-5-ones and analogs exhibiting anti-cancer and anti-proliferative activities. WO2014145023A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported