C-Fms-IN-6

CAT: 0931-T10645-01Size: 25 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T10645-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

1628574-81-1

Target

C-Fms

Related Pathways

Tyrosine Kinase/Adaptors

Bioactivity

C-Fms-IN-6 is a potent inhibitor of c-FMS (IC50 ≤10 nM for unphosphorylated c-FMS) and weakly inhibits unphosphorylated c-KIT and PDGFR (IC50: >1 μM) .

Smiles

O=C1N(N=C(C(C)(C)C)N1)C=2N=C(C)C(OC=3C=C(N=CC3)C4=CN(CC)N=C4)=CC2

Molecular Formula

C22H25N7O2

Molecular Weight

419.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

c-Fms-IN-6

CAS Number	1628574-81-1
PubChem CID	136387335
IUPAC Name	5-tert-butyl-2-[5-[[2-(1-ethylpyrazol-4-yl)-4-pyridinyl]oxy]-6-methyl-2-pyridinyl]-4H-1,2,4-triazol-3-one
Molecular Formula	C22H25N7O2
Molecular Weight	419.5
XLogP	2.7
Topological Polar Surface Area	97.5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	6
Heavy Atom Count	31
Formal Charge	0
Complexity	679

SMILES

CCN1C=C(C=N1)C2=NC=CC(=C2)OC3=C(N=C(C=C3)N4C(=O)NC(=N4)C(C)(C)C)C

InChI

InChI=1S/C22H25N7O2/c1-6-28-13-15(12-24-28)17-11-16(9-10-23-17)31-18-7-8-19(25-14(18)2)29-21(30)26-20(27-29)22(3,4)5/h7-13H,6H2,1-5H3,(H,26,27,30)

InChIKey

NWTRDIYLEGZNSX-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1628574-81-1

CID: 136387335

Formula: C22H25N7O2

MW: 419.5

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	419.5
XLogP3	2.7
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	6
Exact Mass	419.20697307
Monoisotopic Mass	419.20697307
Topological Polar Surface Area	97.5 Å²
Heavy Atom Count	31
Formal Charge	0
Complexity	679
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
T10649-01	C-Fms-IN-3
T10644-01	C-Fms-IN-10
T61589-01	C-Fms-IN-13
T64050-01	C-Fms-IN-12
T10647-01	C-Fms-IN-8
T79815-01	C-Fms-IN-14
T210059-01	C-Fms-IN-15
T10646-01	C-Fms-IN-7
T10643-01	C-Fms-IN-1
T10648-01	C-Fms-IN-9

Alternative Products

Catalog	Name
MBS3843871-01	c-Fms-IN-6
A19416-50	C-Fms-IN-6 50mg
A19416-25	C-Fms-IN-6 25mg
A19416-10	C-Fms-IN-6 10mg
A19416-5	C-Fms-IN-6 5mg
A19416-100	C-Fms-IN-6 100mg
A19416-1	C-Fms-IN-6 1mg
308416-01	C-Fms
BA8861-25	c-Fms-IN-13
BA8846-10	c-Fms-IN-12

C-Fms-IN-6

Chemical Information

Related Products

Alternative Products

Popular Products