c-Fms-IN-15

• UNSPSC Description:

  c-Fms-IN-15 (compound 8g) is a potent inhibitor of FMS kinase, with the IC50 of 563 nM[1].

• Target Antigen:

  c-Fms

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/c-fms-in-15.html

• Smiles:

  O=C(C1=CC(C2=CC=C(NC(NC3=CC=C(N4CCN(C)CC4)C(C(F)(F)F)=C3)=O)C=C2)=NC5=CC=CN=C15)NC

• Molecular Weight:

  563.57

• References & Citations:

  [1]Anusha Sebastian, et al. Design, synthesis, biological evaluation, and in silico studies of novel pyridopyridine derivatives as anticancer candidates targeting FMS kinase. Eur J Med Chem. 2024 Aug 5:274:116557.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3047930-25-3