EBI-1051

CAT: 0804-HY-111368Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-111368Size:1 Each
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Description
EBI-1051 is a highly potent and orally efficacious MEK inhibitor with an IC50 of 3.9 nM.
CAS Number
[1801896-05-8]
UNSPSC
12352005
Target
MEK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/EBI-1051.html
Solubility
10 mM in DMSO
Smiles
O=C(NOC(CO)CO)C1=C(NC2=CC=C(I)C=C2F)C(F)=C3C(C=CO3)=C1
Molecular Formula
C18H15F2IN2O5
Molecular Weight
504.22
References & Citations
[1]Lu B, et al. Discovery of EBI-1051: A novel and orally efficacious MEK inhibitor with benzofuran scaffold. Bioorg Med Chem. 2018 Feb 1;26 (3) :581-589.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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