DSP-1053
CAT:
804-HY-111419-04
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
DSP-1053
- CAS Number: 1176326-76-3
- UNSPSC Description: DSP-1053, a benzylpiperidine derivative, is a potent Serotonin Transporter (SERT) inhibitor with a Ki of 1.02 nM. DSP-1053 shows partial 5-HT1A receptor agonistic activity with a Ki of 5.05 nM. DSP-1053 has antidepressant activity[1].
- Target Antigen: 5-HT Receptor; Serotonin Transporter
- Type: Reference compound
- Related Pathways: GPCR/G Protein;Neuronal Signaling
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/DSP-1053.html
- Purity: 99.72
- Solubility: DMSO : 200 mg/mL (ultrasonic)
- Smiles: BrC1=CC=C(CC2CCN(CCC3=CC(C(CCO4)=O)=C4C=C3)CC2)C=C1OCCOC
- Molecular Weight: 502.44
- References & Citations: [1]Yoshinaga H, et al. Discovery of DSP-1053, a novel benzylpiperidine derivative with potent serotonin transporter inhibitory activity and partial 5-HT1A receptor agonistic activity. Bioorg Med Chem. 2018 May 1;26(8):1614-1627.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: Phase 1