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AH-1058

CAT: 0804-HY-116500ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-116500ASize:1 Each
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Description
AH-1058 is a newly synthesized antiarrhythmic agent that exhibits significant antiarrhythmic activity by delaying premature ventricular complexes and ventricular fibrillation in experimental arrhythmia models. AH-1058 effectively inhibits both ventricular tachycardia and ventricular fibrillation in the reperfusion-induced arrhythmia model in rats. AH-1058 demonstrates potent calcium channel-blocking effects, suppressing L-type Ca2+ currents in isolated cardiomyocytes.
CAS Number
228123-15-7
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ah-1058.html
Smiles
O=[N+]([O-])C1=C(C=CC=C1/C=C/CN2CC/C(CC2)=C3C4=CC=CC=C4C=CC5=CC=CC=C/35)OC.Cl
Molecular Formula
C30H29ClN2O3
Molecular Weight
501.02
References & Citations
[1]Effects of AH-1058, a new antiarrhythmic drug, on experimental arrhythmias and cardiac membrane currents
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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