TG 41

• UNSPSC Description:

  TG 41 is positive modulator of GABAA receptor. TG 41 enhances the binding both of GABA and of Flunitrazepam to rat cerebral cortical membranes[1].

• Target Antigen:

  GABA Receptor

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/tg-41.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CN(C2=CC=C(Cl)C=C2Cl)C(C3=CC=C(Br)C=C3)=N1)OCC

• Molecular Weight:

  440.12

• References & Citations:

  [1]Mascia MP, et al. Ethyl 2-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-4-imidazolecarboxylate is a novel positive modulator of GABAA receptors. Eur J Pharmacol. 2005 Jun 15;516(3):204-11.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  850339-33-2