TG 100713

• Description:

  TG 100713 is an inhibitor of PI3K, with IC50s of 24, 50, 165, and 215 nM for PI3Kδ, γ, α and β isoforms respectively[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  PI3K

• Type:

  Reference compound

• Related Pathways:

  PI3K/Akt/mTOR

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/tg-100713.html

• Purity:

  99.49

• Solubility:

  DMSO : 6.41 mg/mL (ultrasonic)

• Smiles:

  OC1=CC=CC(C2=NC3=C(N)N=C(N)N=C3N=C2)=C1

• Molecular Formula:

  C12H10N6O

• Molecular Weight:

  254.25

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Doukas J, et, al. Phosphoinositide 3-kinase gamma/delta inhibition limits infarct size after myocardial ischemia/reperfusion injury. Proc Natl Acad Sci U S A. 2006 Dec 26;103 (52) :19866-71.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ

• CAS Number:

  [925705-73-3]