TG 100713

• Description :

  TG 100713 is an inhibitor of PI3K, with IC50s of 24, 50, 165, and 215 nM for PI3Kδ, γ, α and β isoforms respectively[1].

• CAS Number :

  [925705-73-3]

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  PI3K

• Type :

  Reference compound

• Related Pathways :

  PI3K/Akt/mTOR

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/tg-100713.html

• Purity :

  99.49

• Solubility :

  DMSO : 6.41 mg/mL (ultrasonic)

• Smiles :

  OC1=CC=CC(C2=NC3=C(N)N=C(N)N=C3N=C2)=C1

• Molecular Formula :

  C12H10N6O

• Molecular Weight :

  254.25

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Doukas J, et, al. Phosphoinositide 3-kinase gamma/delta inhibition limits infarct size after myocardial ischemia/reperfusion injury. Proc Natl Acad Sci U S A. 2006 Dec 26;103 (52) :19866-71.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ