IKK2-IN-3

• UNSPSC Description:

  IKK2-IN-3 (Compound 8) is an IKK2 inhibitor with an IC50 of 0.075 μM[1].

• Target Antigen:

  IKK

• Type:

  Reference compound

• Related Pathways:

  NF-κB

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/ikk2-in-3.html

• Purity:

  98.0

• Solubility:

  DMSO : 10 mg/mL (ultrasonic;warming)

• Smiles:

  O=C(C1=C(OCC2=CC=C(S(=O)(C)=O)C=C2)C=C(N3C4=CC(OC)=C(OC)C=C4N=C3)S1)N

• Molecular Weight:

  487.55

• References & Citations:

  [1]Xie HZ, et al. Pharmacophore modeling and hybrid virtual screening for the discovery of novel IκB kinase 2 (IKK2) inhibitors. J Biomol Struct Dyn. 2011 Aug;29(1):165-79.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  916985-21-2