LY-2087101

• UNSPSC Description:

  LY-2087101 is an allosteric potentiator of α7 nAChRs. LY-2087101 causes potentiation of agonist-evoked α7 responses by binding within the nAChR transmembrane region[1].

• Target Antigen:

  nAChR

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/ly-2087101.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CSC=C1)C2=C(N=C(NC3=CC=C(F)C=C3)S2)C

• Molecular Weight:

  318.39

• References & Citations:

  [1]Gareth T Young, et al. Potentiation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site. Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14686-91.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  913186-74-0