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LY-2087101

CAT: 0804-HY-107683-01Size: 1 mgDry Ice: NoHazardous: No
HY-107683-011 mg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LY-2087101 is an allosteric potentiator of α7 nAChRs. LY-2087101 causes potentiation of agonist-evoked α7 responses by binding within the nAChR transmembrane region[1].
CAS Number
[913186-74-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ly-2087101.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CSC=C1)C2=C(N=C(NC3=CC=C(F)C=C3)S2)C
Molecular Formula
C15H11FN2OS2
Molecular Weight
318.39
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Gareth T Young, et al. Potentiation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site. Proc Natl Acad Sci U S A. 2008 Sep 23;105 (38) :14686-91.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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