SCH 900978

• UNSPSC Description:

  SCH 900978 (NK-1 Antagonist 1) is an antagonist of NK-1 receptor, used in the research of NK-1 related diseases and conditions such as cough, overactive bladder, alcohol dependency and depression[1].

• Target Antigen:

  Neurokinin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Neurological Disease; Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/sch-900978.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@H](C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)OC[C@@]2(C3=CC=CC=C3)CC[C@](C#N)(N4C(NN=C4)=O)CN2

• Molecular Weight:

  539.47

• References & Citations:

  [1]Jane H. Hsiao, et al. Heteroaryl carbonitriles for the treatment of disease. WO2017011445A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 2

• CAS Number:

  873947-10-5