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SCH-900271

CAT: 0804-HY-111143-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-111143-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SCH-900271 is an orally active, potent nicotinic acid receptor (NAR) agonist with an EC50 of 2 nM in the hu-GPR109a assay. SCH-900271 exhibits dose-dependent inhibition of plasma free fatty acid (FFA) . SCH-900271 has an improved therapeutic window to flushing[1].
CAS Number
915210-50-3
UNSPSC
12352005
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/sch-900271.html
Purity
98.64
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C1NC2=C(C(CCCC3(C)CC3)=CC(O2)=O)C(N1)=O
Molecular Formula
C14H16N2O4
Molecular Weight
276.29
References & Citations
[1]Anandan Palani, et al. Discovery of SCH 900271, a Potent Nicotinic Acid Receptor Agonist for the Treatment of Dyslipidemia. ACS Med Chem Lett. 2011 Nov 24;3 (1) :63-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

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