JAK-2/3-IN-1

JAK-2/3-IN-1

• CAS Number: 1036241-36-7
• UNSPSC Description: JAK-2/3-IN-1 is a potent JAK-2 and JAK-3 inhibitor extracted from patent US8163732B2, compound 46, has Kis of [1].
• Target Antigen: JAK
• Type: Reference compound
• Related Pathways: Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
• Applications: COVID-19-immunoregulation
• Field of Research: Cancer; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/jak-2-3-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: OC1=CC=C(C2=NC3=CC=CC=C3C4=C5C(NC=C25)=NC=C4)C(Cl)=C1
• Molecular Weight: 345.78
• References & Citations: [1]Youssef Bennani, et al. Tricyclic heteroaryl compounds useful as inhibitors of Janus kinase. US8163732B2.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported