JAK-2/3-IN-1

CAT: 0804-HY-10652Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-10652Size:1 Each

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Description

JAK-2/3-IN-1 is a potent JAK-2 and JAK-3 inhibitor extracted from patent US8163732B2, compound 46, has Kis of [1].

CAS Number

1036241-36-7

UNSPSC

12352005

Target

JAK

Type

Reference compound

Related Pathways

Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/jak-2-3-in-1.html

Solubility

10 mM in DMSO

Smiles

OC1=CC=C(C2=NC3=CC=CC=C3C4=C5C(NC=C25)=NC=C4)C(Cl)=C1

Molecular Formula

C20H12ClN3O

Molecular Weight

345.78

References & Citations

[1]Youssef Bennani, et al. Tricyclic heteroaryl compounds useful as inhibitors of Janus kinase. US8163732B2.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

JAK2; JAK3

Related Products

Catalog	Name
HY-151256	JAK-2/3-IN-2
HY-151285	JAK-2/3-IN-3
HY-111750-01	JAK-IN-3
HY-13827-01	JAK-IN-1
HY-149283	JAK/HDAC-IN-2
HY-149284	JAK/HDAC-IN-3
HY-156535	JAK kinase-IN-1
HY-126141-01	JAK/HDAC-IN-1
HY-128450-01	JAK-STAT-IN-1
HY-145029	SYK/JAK-IN-1

Alternative Products

Catalog	Name
MBS5799089	JAK-2/3-IN-1
MBS5803611	JAK-2/3-IN-3
MBS5804027	JAK-2/3-IN-2
MBS3844669-01	JAK-IN-3
JDC67353-01	JAK-IN-1
A20220-1	JAK-IN-3 1mg
MBS5820370	JAK/HDAC-IN-2
T86754-01	JAK/HDAC-IN-3

JAK-2/3-IN-1

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