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Eesperamicin A1

CAT: 0804-HY-105237Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-105237Size:1 Each
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Description
Esperamicin A1, as an extremely potent antitumor antibiotic, is isolated from cultures of Actinomadura verrucosospora. Esperamicin A1 can be used for the research of antitumor[1]. Eesperamicin A1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
[99674-26-7]
UNSPSC
12352005
Target
Antibiotic; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/eesperamicin-a1.html
Solubility
10 mM in DMSO
Smiles
CSSSC/C=C1C2=C(C([C@@H](O[C@@]3([H])C[C@@H]([C@H](O)[C@H](C)O3)OC(C4=C(C=C(OC)C(OC)=C4)NC(C(OC)=C)=O)=O)[C@]\1(C#C/C=C\C#C[C@@H]2O[C@@]5([H])[C@@H]([C@H]([C@H](NO[C@H]6C[C@@H]([C@H](SC)[C@@H](C)O6)O)[C@@H](C)O5)O)O[C@@]7([H])C[C@@H]([C@@H](NC(C)C)CO7)OC)O)=O)NC(OC)=O
Molecular Formula
C59H80N4O22S4
Molecular Weight
1325.54
References & Citations
[1]Lam, K. S., et al. Biosynthesis of esperamicin A1, an enediyne antitumor antibiotic. Journal of the American Chemical Society, 115 (26), 12340–12345.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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