Human IgG Immunoglobulin (ICO-97), 1mg/mL

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Description
Recognizes a protein of 75 kDa, identified as Î3 heavy chain of human immunoglobulins. It does not cross-react with α (IgA), Î1⁄4 (IgM), Îμ (IgE), or Î ́ (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
CAS Number
9007-83-4
Synonyms
G1m Marker; G2m Marker; G3m Marker; G4m Marker; HDC; Heavy Chain Disease Protein; Human Immunglobulin G; Ig gamma1/2/3/4 Chain C Region; IGHG1; IGHG2; IGHG3; IGHG4; Immunoglobulin Heavy Constant 1/2/3/4
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
IGHG
Gene ID
3500 (IGHG1), 3501 (IGHG2), 3502 (IGHG3), 3503 (IGHG4)
NCBI Gene ID
510635
UniProt
P01857, P01859, P01860, P01861
Swiss Prot
P01857, P01859, P01860, P01861
Host
Mouse
Species Reactivity
Human
Reactivity
Human IgG
Immunogen
Purified human Ig Gamma Chain
Target Antigen
Human IgG
Clonality
Monoclonal
Clone
ICO-97
Type
Anti-Human Immunoglobulin|Primary
Source
Animal
Origin
Animal
Field of Research
Cancer, Immunology, Inflammation
Positive Control
293T, Raji or hPBL cells. Tonsil or Spleen
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
75 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free
Product Datasheet
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