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Obscurolide A1

CAT: 0804-HY-125738Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-125738Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Obscurolide A1 is a Phosphodiesterase (PDE) inhibitor (IC50=8 mM) that can be obtained from Streptomyces viridochromogenes culture. Obscurolide A1 has the potential to study neurological and inflammatory diseases[1].
CAS Number
144397-99-9
UNSPSC
12352005
Hazard Statement
H302+H312+H332-H319
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/obscurolide-a1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(C=C1)NC(C(O2)/C=C/C(C)O)CC2=O)O
Molecular Formula
C15H17NO5
Molecular Weight
291.30
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Hoff H, et al. Metabolic products of microorganisms. 261. Obscurolides, a novel class of phosphodiesterase inhibitors from streptomyces. I. Production, isolation, structural elucidation and biological activity of obscurolides A1 to A4. J Antibiot (Tokyo) . 1992 Jul;45 (7) :1096-107.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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