DPNI-GABA

• Description:

  DPNI-GABA is a nitroindoline cage compound that inhibits GABA (A) receptors and reduces GABA-evoked peak responses with an IC50 value of 0.5 mM[1].

• UNSPSC:

  12352005

• Target:

  GABA Receptor

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/dpni-gaba.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C (N1CCC2=C1C ([N+] ([O-]) =O) =CC=C2OC (COP (O) (O) =O) COP (O) (O) =O) CCCN

• Molecular Formula:

  C15H23N3O12P2

• Molecular Weight:

  499.30

• References & Citations:

  [1]Trigo FF, et al. Laser photolysis of DPNI-GABA, a tool for investigating the properties and distribution of GABA receptors and for silencing neurons in situ. J Neurosci Methods. 2009 Jul 30;181 (2) :159-69.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  927866-58-8