DPNI-GABA

• UNSPSC Description:

  DPNI-GABA is a nitroindoline cage compound that inhibits GABA(A) receptors and reduces GABA-evoked peak responses with an IC50 value of 0.5 mM[1].

• Target Antigen:

  GABA Receptor

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/dpni-gaba.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N1CCC2=C1C([N+]([O-])=O)=CC=C2OC(COP(O)(O)=O)COP(O)(O)=O)CCCN

• Molecular Weight:

  499.30

• References & Citations:

  [1]Trigo FF, et al. Laser photolysis of DPNI-GABA, a tool for investigating the properties and distribution of GABA receptors and for silencing neurons in situ. J Neurosci Methods. 2009 Jul 30;181(2):159-69.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  927866-58-8