DPNI-GABA

• Description :

  DPNI-GABA is a nitroindoline cage compound that inhibits GABA (A) receptors and reduces GABA-evoked peak responses with an IC50 value of 0.5 mM[1].

• UNSPSC :

  12352005

• Target :

  GABA Receptor

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/dpni-gaba.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(N1CCC2=C1C([N+]([O-])=O)=CC=C2OC(COP(O)(O)=O)COP(O)(O)=O)CCCN

• Molecular Formula :

  C15H23N3O12P2

• Molecular Weight :

  499.30

• References & Citations :

  [1]Trigo FF, et al. Laser photolysis of DPNI-GABA, a tool for investigating the properties and distribution of GABA receptors and for silencing neurons in situ. J Neurosci Methods. 2009 Jul 30;181 (2) :159-69.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [927866-58-8]