GABA-IN-4

• Description:

  GABA-IN-4 (Compound 17) is a N- (indol-3-ylglyoxylyl) benzylamine derivative. GABA-IN-4 exhibits high affinity for the benzodiazepine receptor (BzR) (binding site in GABAA receptor complex) with Ki value of 67 nM. Benzodiazepines are widely used as antianxiety, sedative-hypnotic and anticonvulsant agents[1].

• UNSPSC:

  12352101

• Target:

  GABA Receptor

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research:

  Neurological Disease

• Smiles:

  O=C(C(C1=CNC2=C1C=CC=C2)=O)NCC3=CC=C(C=C3)Cl

• Molecular Formula:

  C17H13ClN2O2

• Molecular Weight:

  312.75

• References & Citations:

  [1]Da Settimo A, et al. Synthesis, structure-activity relationships, and molecular modeling studies of N- (indol-3-ylglyoxylyl) benzylamine derivatives acting at the benzodiazepine receptor. J Med Chem. 1996 Dec 20;39 (26) :5083-91.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [61-38-1]