SB 268262

CAT: 0804-HY-103304Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-103304Size:5 mg
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Description
CGRP antagonist 4 is an antagonist of calcitonin gene-related peptide (CGRP) receptor. CGRP antagonist 4 shows the highest affinity for CGRP receptors in the human brain. CGRP antagonist 4 can be used to study the binding properties of non-peptide calcitonin gene-related peptide (CGRP) receptor antagonist (gepants) in rat, pig and human menes [1].
CAS Number
[217438-17-0]
UNSPSC
12352005
Hazard Statement
H302, H319
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cgrp-antagonist-4.html
Purity
99.9
Solubility
10 mM in DMSO
Smiles
O=C(N(C)C1=CC=CC=C1C)C2=CC=C(S(C3=NC=CS3)=O)C([N+]([O-])=O)=C2
Molecular Formula
C18H15N3O4S2
Molecular Weight
401.46
Precautions
H302, H319
References & Citations
[1]Warfvinge K, et al. The Presence of Calcitonin Gene-Related Peptide and Its Receptors in Rat, Pig and Human Brain: Species Differences in Calcitonin Gene-Related Peptide Pharmacology. Pharmacology. 2019;104 (5-6) :332-341.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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