LY-517717

• Description:

  LY-517717 is a potent and orally active FXa inhibitor. LY-517717 shows antithrombotic and anticoagulant activity. LY-517717 has the potential for the research of venous thromboembolism after hip or knee replacement[1].

• UNSPSC:

  12352005

• Target:

  Factor Xa

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/ly-517717.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N1CCN(C2CCN(C)CC2)CC1)[C@@H](C3=CC=CC=C3)NC(C(C=C4)=CC5=C4C=CN5)=O

• Molecular Formula:

  C27H33N5O2

• Molecular Weight:

  459.58

• References & Citations:

  [1]Agnelli G, et al. A phase II study of the oral factor Xa inhibitor LY517717 for the prevention of venous thromboembolism after hip or knee replacement. J Thromb Haemost. 2007 Apr;5 (4) :746-53.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• CAS Number:

  [313489-71-3]