D-Cl-amidine

D-Cl-amidine

• CAS Number: 1404060-15-6
• UNSPSC Description: D-Cl-amidine is a potent and highly selective PAD1 inhibitor. D-Cl-amidine is well-torelated with no significant toxicity[1].
• Target Antigen: Apoptosis; Protein Arginine Deiminase
• Type: Reference compound
• Related Pathways: Apoptosis;Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: Cancer; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/d-cl-amidine.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N[C@@H](C(N)=O)CCCNC(CCl)=N)C1=CC=CC=C1
• Molecular Weight: 310.78
• References & Citations: [1]Bicker KL, et al. D-amino acid based protein arginine deiminase inhibitors: Synthesis, pharmacokinetics, and in cellulo efficacy. ACS Med Chem Lett. 2012 Oct 26;3(12):1081-1085.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported