D-Cl-amidine

• Description:

  D-Cl-amidine is a potent and highly selective PAD1 inhibitor. D-Cl-amidine is well-torelated with no significant toxicity[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis; Protein Arginine Deiminase

• Type:

  Reference compound

• Related Pathways:

  Apoptosis; Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/d-cl-amidine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C (N[C@@H] (C (N) =O) CCCNC (CCl) =N) C1=CC=CC=C1

• Molecular Formula:

  C14H19ClN4O2

• Molecular Weight:

  310.78

• References & Citations:

  [1]Bicker KL, et al. D-amino acid based protein arginine deiminase inhibitors: Synthesis, pharmacokinetics, and in cellulo efficacy. ACS Med Chem Lett. 2012 Oct 26;3 (12) :1081-1085.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1404060-15-6