BB-Cl-Amidine (hydrochloride)

• UNSPSC Description:

  BB-Cl-Amidine hydrochloride is a peptidylarginine deminase (PAD) inhibitor[1].

• Target Antigen:

  Protein Arginine Deiminase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/bb-cl-amidine-hydrochloride.html

• Purity:

  99.47

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)|H2O : 5 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C(C1=CC=C(C2=CC=CC=C2)C=C1)N[C@H](C3=NC4=CC=CC=C4N3)CCCNC(CCl)=N.Cl

• Molecular Weight:

  496.43

• References & Citations:

  [1]Knight JS, et al. Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice. Ann Rheum Dis. 2015 Dec;74(12):2199-206.Nat Cell Biol. 2021 Oct 6.|Nat Commun. 2024 Sep 3;15(1):7654.|Oncol Rep. 2023 Jul;50(1):146.|Res Sq. 2024 Jun 04.|Cell Physiol Biochem. 2024 Feb 19;58(1):63-82.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  2436747-41-8