BB-Cl-Amidine

BB-Cl-Amidine

• CAS Number: 1802637-39-3
• UNSPSC Description: BB-Cl-Amidine is a peptidylarginine deminase (PAD) inhibitor.
• Target Antigen: Protein Arginine Deiminase
• Type: Reference compound
• Related Pathways: Epigenetics
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/BB-Cl-Amidine.html
• Purity: 95.03
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C(C1=CC=C(C2=CC=CC=C2)C=C1)N[C@H](C3=NC4=CC=CC=C4N3)CCCNC(CCl)=N
• Molecular Weight: 459.97
• References & Citations: [1]Knight JS, et al. Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice. Ann Rheum Dis. 2015 Dec;74(12):2199-206.Cell Physiol Biochem. 2024 Feb 19;58(1):63-82.|Nat Cell Biol. 2021 Oct 6.|Nat Commun. 2024 Sep 3;15(1):7654.|Oncol Rep. 2023 Jul;50(1):146.|Res Sq. 2024 Jun 04.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, stored under nitrogen)
• Clinical Information: No Development Reported